Perczel András
D.Sc., full professor


1518 Budapest 112, Pf.: 32, Hungary
+36-1-372-2500 / 1653

Short CV:

Born: 1959.

MSc: 1985, PhD: 1988

CSc: 1992, DSc: 1998

CMHAS: 2010

Employment: 1993-98: associate research professor, 1998-2001: research professor, 2001: full professor, 2007: head of the Dept. of Organic Chemistry at the Institute of Chemistry, Eötvös Loránd University

Teaching experience

  • 1985-94 Organic chemistry laboratory courses
  • 1994- Structural investigation of peptides and proteins (optional course)
  • 1996-2001 Organic chemistry laboratory courses
  • 1997- NMR pulse sequences in structure determination (optional course)
  • 2001- Organic chemistry for biologists (lectures)
  • 2003- Theoretical organic chemistry (lectures)
  • 2008- Biological chemistry (lectures)

Research interests:

  • Synthesis of peptides on solid phase and using biotechnology
  • Spectroscopic analysis (CD, NMR) of bioactive peptides
  • Structure and stability of α- and β-peptides, their nanofibril-forming and aggregation potency
  • Protein bioNMR: structure, dynamics and function in glubular and disordered (IUP) systems
  • Mapping protein-ligend interactions. Structural investigations on biologically important systems.
Structural Chemistry and Biology Laboratory
ELTE-MHAS protein modelling group


More than 170 papers in international journals with over 2100 independent citations, three book chapters, two reviews and one book (in Hungarian)

Awards: Pro Scientia gold medal 1993 and 1995 (form the Hungarian Acad. of Sci.), Zemplén Géza award 1996 ( form the Hungarian Acad. of Sci.), Scientific award (1st price) in 1997 (form the Faculty of Science L. Eötvös. Univ.), Széchényi Professor form 1998-, Széchényi Professor form 1998-2002, Scientist of the year, Sanofi-Synthelabo, 2004

Five selected publications:

  • Péter Hudáky, Pál Stráner, Viktor Farkas, Györgyi Váradi, Gábor Tóth, András Perczel:
    Cooperation between a salt bridge and the hydrophobic core triggers fold stabilization in a Trp-cage miniprotein
    Biochemistry (2008) 47:1007-1016.
  • András Perczel, Péter Hudáky and Villő Pálfi:
    Dead-end street of protein folding: thermodynamic rationale of amyloid fibril formation
    J. Am. Chem. Soc. (2007) 129:14959-14965
  • Charles D. Blundell, David J. Mahoney, Martin R. Cordell, Andrew Almond, Jan D. Kahmann, András Perczel, Jonathan D. Taylor, Iain D. Campbell and Anthony J. Day:
    Determining the molecular basis for the pH-dependent interaction between the Link module of human TSG-6 and hyaluronan
    J. Biol. Chem. (2007) 282:12976-12988.
  • Gábor Pohl, Tamás Beke, János Borbély and András Perczel:
    Prediction of folding preference of 10kDa silk-like proteins using a lego-approach and ab initio calculations
    J. Am. Chem. Soc. (2006) 128:14548-14559
  • Tamás Beke, Imre G. Csizmadia and András Perczel:
    Theoretical study on tertiary structural elements of β-peptides: Nanotubes formed from parallel-sheet-derived assemblies of β-peptides
    J. Am. Chem. Soc. (2006) 128:5158-5167.

last modified: Tue Oct 13 15:34:55 CET 2009