Research
Focus:
Development
and application of computational methods for molecular
modeling:
Develop high
throughput methods for conformational search of flexible molecules
and/or molecular libraries (e.g.: a set of linear oligopeptides).
Based
on the theoretically obtained distribution of conformers and experimental
binding results, we establish a relationship between conformations
and activity, resulting in a prediction of active structures.
Application
of computational methods ranging from molecular dynamics simulations
to ab inito studies for the purpose of solving questions of chemical
interest.
Personal Data:
Date
of Birth: 4. February 1978
Place of Birth: Salgótarján, Hungary
Citizenship: Hungarian
Education:
Ph.D.
in Chemistry, Eötvös University of Budapest, Hungary, 2005 (expected)
Thesis: Calculation Methods for Exploring Conformational Properites
of Flexible Oligopeptides (expected) Research Director: Prof. Ö.
Farkas
M.Sc.
Chemistry, Eötvös University of Budapest, Hungary, 2001
Thesis: Design, Synthesis and Exploration of Conformation space
of Oligotuftsin Based Drug Carriers Research Directors: Prof G.
Mező, Prof. Ö. Farkas
Fellowships:
Visiting
scientist at Wayne State University, Detroit, MI, USA (2002)
Research Director: Prof. Bernhard Schlegel
Erasmus
Fellowship to University of Konstanz, Germany (2001)
Research Director: Prof. Dr. Clemens Richert
Conferences:
27th
European Peptide Symposium (2002) Poster presentation:
Conformation Characterization of Flexible Oligopeptides
Competitions :
National
Scientific Competition in Chemistry for University Students, Hungary,
(2001)
Scientific
Competition in Chemistry at Eötvös University, Hungary (2000)
ESE96
The First European Science Fair for Youth, Prague, Czech Republic
(1996)
Selected Posters and Publications
G.
Mező, A. Kalászi, J.Reményi, N. Mihala, Zs.Majer, Á. Hilbert,
O. Láng, L. Kőhidai, K. Barna, D. Gaál: Synthesis of new carrier
molecules based on repeated tuftsin sequences. 26th European Peptide
Symposium, Montpellier (2000).
Mezô,
G., Kalászi, A., Reményi, J., Gaál, D., Hilbert, Á., Hudecz,
F.: Synthesis and application of tuftsin oligomers as carrier molecules.
COST Chemistry Action D13, New Molecules Towards Human Health Care,
Mid-Term Evaluation Workshop, April 26-28, 2001, Athens, Greece
G.
Mező, A. Kalászi, J.Reményi, N. Mihala, Zs.Majer, Á. Hilbert,
O. Láng, L. Kőhidai, K. Barna, D. Gaál: Synthesis of new carrier
molecules based on repeated tuftsin sequences. J. Peptide Science
6S, p99. (2000)
